A nonsense mutation is a genetic mutation in a DNA sequence that results in a shorter, unfinished protein product. DNA is a chain of many smaller molecules called nucleotides. During protein ...

A new study suggests genetic changes allow horses to produce more energy, while minimizing the toll the energy takes on cells ...

Many human diseases are caused by point mutations that affect RNA splicing. It has been observed that nonsense mutations that generate premature termination of translation products can drive the use ...

Discover how an emerging technology called tRNA therapy could become the next big thing in genetic disease treatment.

A genetic change that boosts a cell's aerobic capacity while also protecting it from excess stress could explain how horses became such powerful athletes, according to a new study in Science.

A nonsense mutation is an alteration in the genetic code that prematurely halts the synthesis of an essential protein. The resulting disorder is determined by which protein cannot be expressed in ...

Additionally 2 novel missense mutations (E188D, S206I), 1 novel nonsense mutation (Glu237STOP), and 2 known polymorphisms (A318A, L346L) in the NPHS2 gene were found in 38 SSNS and 22 SRNS patients.