Paraneoplastic syndromes are rare cancer-related disorders in which symptoms are caused by the body’s immune response to the tumor or by substances the tumor secretes, such as autoantibodies, ...

Background Relatively few studies have searched for potentially pathogenic antibodies in non-paraneoplastic patients with cerebellar ataxia. Methods and Results We first screened sera from 52 ...

Background Relatively few studies have searched for potentially pathogenic antibodies in non-paraneoplastic patients with cerebellar ataxia. Methods and Results We first screened sera from 52 ...

The following is a summary of “Anti-RGS8 paraneoplastic cerebellar ataxia is preferentially associated with a particular subtype of Hodgkin’s lymphoma,” published in the August 2024 issue of Neurology ...

The cause of the condition is unknown. It leads to dementia and ataxia. Paraneoplastic syndromes: Certain cancers, particularly ovarian cancer, can cause the production of antibodies (immune proteins) ...

Spinocerebellar ataxias (SCA) and Friedreich ataxia (FA) are rare neurodegenerative conditions affecting the cerebellum, primarily manifesting as progressive loss of motor skills, but also involving ...

We report a case of BRAF-mutation positive Erdheim-Chester disease presenting with a cerebellar ataxia. This is the first such case to be reported without structural MRI abnormalities but with a ...

Ataxia is a lack of muscle coordination that can make speech and movement difficult. It may develop due to genetic factors, alcohol use, or injury. It can also stem from a medical condition such ...

In the acute stage, ataxia can cause an inability to walk due to both trunk and limb ataxia. Although opsoclonus and myoclonus are the most noticeable symptoms, they may not always be present.

Eye manifestations of the dermal paraneoplastic syndromes are not well known for the clinician, although a number of cases have already been reported. Ocular changes appear both on the anterior or ...

In cancer, ataxia isn’t a direct reflection of the disease itself, but rather a side effect of the immune response to cancer, known as a paraneoplastic syndrome.