Neutrophils' mitochondrial sensing disrupted in lupus patients, study finds
Assistant Professor Andrew Monteith's lab in the Department of Microbiology is documenting how key immune cells detect ...
Nature16d
Toll-like receptors and phagosome maturation
As the phagosome is the key organelle for the degradation of microbes and for the generation of bacterial peptides to be presented to lymphocytes, this issue is fundamental for understanding the ...
Frontiers3d
Mechanisms and Innovations in Combating Intracellular Infections
These include altering phagosome maturation, resisting oxidative stress, and forming protective niches within host cells. The host initially detects these pathogens through pattern recognition ...
Frontiers22d
Protein phosphorylation in neurodegeneration: friend or foe?
In this situation the normal cellular quality-control systems (molecular chaperones, ubiquitin proteasome system (UPS), phagosome/lysosome system) are not able to counteract and prevent or reverse ...
University of Sheffield5d
Dr Alison Twelvetrees
2021 – present, Sir Henry Dale Fellow, Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield, UK 2017 - 2020, Vice Chancellor’s Fellow, Sheffield Institute for ...
eLife20d
Rab10 inactivation promotes AMPAR trafficking and spine enlargement during long-term potentiation
This is an important study that describes the development of optical biosensors for various Rab GTPases and explores the contributions of Rab10 and Rab4 to structural and functional plasticity at ...
C&EN8d
Siglec-14-Mediated Inflammatory Responses to Carbon Nanomaterials
Laboratory of Immunology and Microbiology, College of Pharmaceutical Sciences, Ritsumeikan University, Kusatsu 525-8577, Japan ...
C&EN15d
Systematic Model Peptide Studies: A Crucial Step To Understand the Coordination Chemistry of Mn(II) and Fe(II) in Proteins
Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator.