She had swelling in both legs and ankles, and her motor strength in all extremities was 2/5, with proximal muscle weakness. Laboratory analysis showed elevated creatine kinase and myoglobin.

What is the differential diagnosis for a formerly active and healthy 70-year-old woman with worsening proximal weakness, torticollis, and a widespread raised red rash across her cheeks bilaterally?

A 44-year-old woman with rheumatoid arthritis was evaluated because of proximal muscle weakness and myalgia. She had difficulty raising her arms above her head. Diagnostic tests were performed.

Muscle weakness is a common presenting symptom in patients with DM, with a subacute onset with gradually progressive symmetric proximal muscle weakness involving the shoulders, hips, and neck muscles.

In patients with proximal muscle weakness, the need for reflexive EMG followed by biopsy is negated if there is (1) presence of colchicine, (2) creatinine clearance <50 mL/min with or without ...

“The closest mimics of myositis are those illnesses characterized by proximal muscle weakness, myopathy and elevated creatine kinase (CK), including inclusion body myositis (IBM) and limb-girdle ...

The most prominent manifestations of SMA are proximal muscle weakness and atrophy. However, the phenotypic classification should not be taken as compartmentalizing the types into discrete categories.

Immune-mediated necrotizing myopathy typically presents with progressive symmetrical proximal muscle weakness and myalgias, although some cases can present with respiratory and esophageal muscle ...

Muscle weakness is more common in men, but if women experience it, it will mainly affect the proximal muscles (those closest to the center of the body). What causes dermatomyositis?

This is a milder form of SMA that typically develops after the age of 21 and is associated with mild to moderate proximal muscle weakness. Other, less common forms of SMA exist, but they occur due ...