The San Francisco 49ers take on the Houston Texans at 10 a.m. PT on Sunday, Oct. 26 at NRG Stadium in Houston.

49ers 24, Texans 16: San Francisco may be without defensive pillars Nick Bosa and Fred Warner, but the Houston offense has ...

The San Francisco 49ers have a better record than the Houston Texans, but the oddsmakers have the Texans as favorites. They ...

Facing a team with a 2-4 record would typically be favorable the San Francisco 49ers. However, the Houston Texans aren't a ...

San Francisco 49ers quarterback Brock Purdy has been ruled out for his team's Week 8 matchup against the Houston Texans amid ...

San Francisco's been without its top wideout for the whole regular season. Here's what we know about his potential return.

While battling injuries all season long, nothing has changed for QB Brock Purdy and WR Ricky Pearsall for the San Francisco ...

The 49ers' top quarterback has missed five of seven games this season so far. Here's the latest on his status for Week 8.

Quarterback Brock Purdy will miss his fourth straight game for the San Francisco 49ers because of a toe injury.

San Francisco 49ers head coach Kyle Shanahan revealed on Friday that the team could open the 21-day practice window of wide ...

With starter Brock Purdy slowly working his way back from the right big toe injury that's kept him out since Week 4, the ...

Despite being one of the most banged-up teams in the NFL, San Francisco sits tied atop the NFC West with the Seahawks and the ...