Background Previous natural history studies highlighted a consistent heterogeneity of disability trajectories among ...

We analysed clinical trials of pharmacological interventions on patients with amyotrophic lateral sclerosis (ALS), and compared study quality and design features. The systematic review included ...

Background: Efficient neuropsychological tests are needed to measure cognitive impairment in moderate to severe dementia. Objective: To examine construct validity of the Severe Impairment Battery ...

Department of Clinical Neurosciences, University of Cambridge Clinical School, Addenbrooke’s Hospital, Cambridge CB2 0QQ, UK N Robertson, Helen Durham Neuro-inflammatory Centre, Department of ...

Objective: Parkinson’s disease (PD) is a progressive neurological disorder characterised by a large number of motor and non-motor features that can impact on function to a variable degree. This review ...

Department of Neuropathology, National Hospitals for Nervous Diseases, London, UK. The Lewy body is a distinctive neuronal inclusion that is always found in the substantia nigra and other specific ...

Dr R Barber, Institute for the Health of the Elderly, Newcastle General Hospital, Westgate Road, Newcastle upon Tyne, NE4 6BE, U.K. Tel +(0)191 256 3274 ext. 22986; fax +(0)191 219 5048; email ...

Correspondence to: Ryuji Sakakibara Department of Neurology Chiba University, 1-8-1 Inohana Chuo-ku, Chiba 260-8670 Japan; sakakibarafaculty.chiba-u.jp If you wish to reuse any or all of this article ...

A unique disorder is described in seven members of two families in whom dystonia was variably associated with subacute visual loss or asymptomatic optic atrophy, and striking bilateral symmetrical ...

Background: Epidemiological research on the incidence of traumatic head injuries relies on the correct definition and classification of the injury. Objective: To address the use of diagnostic criteria ...

Correspondence to Professor Yoon-Ho Hong, Neurology, Neuroscience Research Institute, Medical Research Council, Seoul National University College of Medicine, Seoul Metropolitan Government Boramae ...