Journal of Neurology, Neurosurgery and Psychiatry (JNNP)

Current Issue

Short report: Cluster analysis showed long-term cognition can be predicted by looking at regional grey matter atrophy in the ...
BMJ

Distinct behavioural profiles in frontotemporal dementia and semantic dementia

OBJECTIVE To test predictions that frontotemporal dementia and semantic dementia give rise to distinct patterns of behavioural change. METHODS An informant based semistructured behavioural interview, ...
BMJ

Fixed and dilated pupils after trauma, stroke, and previous intracranial surgery: management and outcome

OBJECTIVES To clarify whether different causative events (trauma, stroke, intracranial surgery), time of intervention, and treatment mode influence outcome, patients with fixed and dilated pupils ...
BMJ

The impact of delays in computed tomography of the brain on the accuracy of diagnosis and subsequent management in patients with minor stroke

Correspondence to: Professor J Wardlaw, Department of Clinical Neurosciences, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK; jmw{at}skull.dcn.ed.ac.uk Objectives: To determine the ...
BMJ

Impact of early intervention on outcome following mild head injury in adults

Background: The impact of mild head injury is variable and determinants of outcome remain poorly understood. Results of previous intervention studies have been mixed. Objectives: To evaluate the ...
BMJ

Neurological immune-related adverse events with checkpoint inhibitor therapy: challenges for the neurologist

Immune checkpoint inhibitors (ICI) have had a dramatic effect on cancer outcomes with their use increasing as indications expand. Despite impressive efficacy across a range of tumour types, their role ...
BMJ

Hippocampal dysfunction defines disease onset in Huntington's disease

Background Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder characterised by a triad of motor, psychiatric and cognitive deficits with the latter classically attributed to ...
BMJ

Mayo and NINDS scales for assessment of tendon reflexes: between observer agreement and implications for communication

a Department of Neurology, b Department of Clinical Epidemiology, Utrecht University Hospital, Utrecht, The Netherlands Professor J van Gijn, University Department of Neurology, Academic Hospital, ...
BMJ

Botulinum toxin and spasticity

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BMJ

Prolonged survival in motor neuron disease: a descriptive study of the King’s database 1990–2002

MND Care and Research Clinic, King’s College London, UK Correspondence to: Dr A Al-Chalabi, MND Care and Research Clinic, PO41 (ANC), Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK; ...
BMJ

Interleukin 18 gene polymorphisms predict risk and outcome of Alzheimer’s disease

Background and aim: Inflammation has been extensively implicated in the pathogenesis of Alzheimer’s disease (AD). Although there is evidence of a key role for cytokines in neuroinflammation processes, ...