2 Minute Medicine

Early menarche and later menopause are associated with increased ovarian cancer risk

Across the premenopausal and postmenopausal groups, early menarche, later menopause, and longer reproductive span were associated with higher ovarian cancer risk, while parity was associated with ...
2 Minute Medicine

A telephone-based intervention reduced loneliness and improved well-being among older adults

Four weeks of telephone-delivered behavioral activation and mindfulness interventions by lay counsellors were associated with reduced loneliness and improved well-being at 12 months among older adults ...
2 Minute Medicine

Propofol is associated with lower mortality in sepsis-associated encephalopathy

Among patients with sepsis-associated encephalopathy, propofol monotherapy was associated with lower one-year all-cause ...
2 Minute Medicine

The Scan by 2 Minute Medicine®: Daily caffeine intake linked to lower dementia risk, AAP sues over federal vaccine schedule overhaul, Catherine O’Hara passes away after ...

The Scan by 2 Minute Medicine® is a pop-culture medical newsletter and exclusive benefit for 2 Minute Medicine Plus subscribers. Moderate caffeine intake linked to significantly lower dementia risk ...
2 Minute Medicine

Polypharmacy is associated with higher risk of mortality and hospitalizations among older adults

Polypharmacy was associated with a higher risk of mortality and hospitalization at one-year and five-years among older adults aged >75 years. Evidence Rating Level: 2 (Good) Polypharmacy is commonly ...
2 Minute Medicine

Oral nonstatin medication significantly lowers cholesterol in high-risk patients

In this randomized controlled trial, once-daily oral enlicitide was associated with sustained reductions in low-density lipoprotein cholesterol levels compared to placebo among those at high risk of ...
2 Minute Medicine

Status epilepticus cause may predict likelihood of neurologic recovery but not short-term mortality

The underlying cause of status epilepticus is strongly associated with the likelihood of neurologic recovery, but does not independently predict short-term mortality. 2. Nonconvulsive status ...
2 Minute Medicine

The incidence of psychotic disorders has increased in more recent birth cohorts

The incidence of psychotic disorders in Ontario has increased in more recent birth cohorts, and the age of diagnosis has ...
2 Minute Medicine

An ultrasound test may more reliably detect ovarian cancer in premenopausal women than the Risk of Malignancy Index

This cohort study found that the IOTA ADNEX ultrasound model at a 10% risk threshold detected more ovarian cancers in premenopausal women than the currently used Risk of Malignancy Index, making it a ...
2 Minute Medicine

Chimeric antigen receptor T-cell therapy may induce sustained remission in multirefractory autoimmune hemolytic anemia

In this prospective cohort study, CD19-directed chimeric antigen receptor (CAR) T-cell therapy was found to elicit a complete ...
2 Minute Medicine

Neonatal Hyperbilirubinemia and navigating the 2022 AAP guideline updates

The 2022 American Academy of Pediatrics guidelines slightly raised phototherapy thresholds for most infants to balance preventing encephalopathy with avoiding the harms of over treatment: This update ...
2 Minute Medicine

Knee bracing may provide small improvements in patient-reported outcomes in knee osteoarthritis

Adding compartment-specific knee bracing with an adherence support intervention to standard advice, information and exercise ...