We wanted to find out if oral nicotine pouches can help people transition away from smoking, nicotine vaping, or other forms of tobacco use. We also wanted to know if oral nicotine pouches caused any ...

Epilepsy is a brain condition that causes seizures. It affects around one in 1000 children under five years old, and around one in 200 children between five and 19 years old. In a seizure, the brain's ...

The effect of oral riboflavin (vitamin B 2) supplements on blood pressure is uncertain. Large, well-conducted trials are needed to assess the effect of riboflavin on blood pressure lowering.

We do not know if medicinal and non-medicinal treatments help reduce impulsive-compulsive behaviors in people with Parkinson's disease because the currently available evidence is limited and uncertain ...

Simple hysterectomy may result in little to no difference in the number of deaths from any cause, life expectancy after treatment, deaths from cancer, cancer-free period after treatment, or the rate ...

Why systematic and rigorous searches are important, planning and designing search strategies, sources of studies, managing and reporting the process.

Our Handbooks describe the process of preparing and maintaining diverse types of systematic reviews. Handbooks are updated regularly to reflect advances in systematic review methods and in response to ...

To speak to the a member of the Cochrane Collaboration press office: If you would like to be added to our mailing lists for press releases about new Cochrane reviews, just send us an email. We can ...

Cochrane Evidence Essentials is an introduction to evidence-based medicine, clinical trials and Cochrane evidence. It is designed for patients and the public, policy makers and members of healthcare ...

Here we list specialized resources for other methods that Cochrane Groups have produced. Clinical study reports and other regulatory documents Clinical study reports (CSRs) are documents submitted to ...

Due to a lack of robust evidence, the benefits and risks of adding chemotherapy directly into the abdominal cavity (intraperitoneal chemotherapy, or IPC) for stomach cancer are unclear.

• Blood pressure-lowering medications lower the chance of death and probably reduce heart attacks and strokes in people with hypertension (high blood pressure) 60 years of age or older. • There may be ...