Most cells in the human body each contain about six feet of DNA. Yet the nucleus, where DNA is coiled, is no larger than a ...

Instead, it forms a pliable, inconsistent chain characterized by a wide variety of folding patterns. “We show that chromatin does not need to form discrete higher-order structures to fit in the ...

Kanazawa University and colleagues have achieved a breakthrough in understanding sperm DNA packaging. Using high-speed atomic ...

An international team of researchers co-led by Job Dekker, Ph.D., at UMass Chan Medical School, have identified rules that ...

Some DNA viruses are known to alter chromatin folding, suppressing immune genes such that they can infect cells more readily. But it was long unclear whether RNA viruses, including SARS-CoV-2, perform ...

Kanazawa University and colleagues have achieved a breakthrough in understanding sperm DNA packaging. Using high-speed atomic force microscopy (HS-AFM), they captured the real-time process of ...