The common conception of DNA is in long, twisting strands, but in order to fit into the confines of the nucleus, DNA actually condenses into a strict structure called chromatin. Chromatin facilitates ...

In eukaryotes, DNA is tightly wound into a complex called chromatin. Thanks to the process of chromatin remodeling, this complex can be "opened" so that specific genes are expressed.

Many mechanisms have been proposed to explain how chromatin is segregated within the nucleus, however none of them were conclusive, largely, ...

Inside a nucleus, chromosomes jumble together like a game of Twister. This can bring regulatory elements, such as enhancers, from one chromosome into contact with genes from another chromosome, ...

The scientists observed that chromatin self-organizes into "packing domains"—distinct, compact regions of molecular structures that play a crucial role in regulating gene expression.

A multidisciplinary team of Indiana University researchers have discovered that the motion of chromatin, the material that DNA is made of, can help facilitate effective repair of DNA damage in the ...

Inside cells, DNA mixes with proteins to form chromatin within the nucleus. Within chromatin, structures called packing domains form when chromatin fibers fold together.

Cells depend on the precise reading of DNA sequences to function correctly. This process, known as gene expression, ...

But archaea do not have a nucleus, and their small circular genomes are easier to package inside their cells. “If the primary role for chromatin is not packaging, it might instead be to regulate gene ...

Red cell nucleus, green cytoskeleton: in microscopic images like this one, the AI developed at PSI recognizes the finest changes in chromatin – and thus genetic disorders.

Researchers discover a way to observe chromatin interaction changes in cancer ... "Sometimes you can't see or predict all the other things that are likely to happen in the machine of the nucleus.