Macrophages accumulate free cholesterol in advanced atherosclerotic lesions, resulting in macrophage apoptosis and progression of lesions 1,2,3,4,5,6,7,8. Previous studies with cultured macrophages ...

Paul Victor, Dhamodharan Umapathy, Leema George, Udyama Juttada, Goutham V. Ganesh, Karan Naresh Amin, Vijay Viswanathan and Kunka Mohanram Ramkumar Increasing evidence in substantiating the roles of ...

Aging involves a balance between oxidants and antioxidants, low-grade inflammation and a protein response that occurs at the cellular level, which is responsible for many health disorders. Exercise ...

Exercise is known for the positive effects on metabolic diseases, partly because of the release of circulating extracellular ...

After their co-translational insertion into the ER lumen or the ER membrane, most proteins are transported via the Golgi apparatus downstream on the secretory pathway while a few protein species are ...

When a wound on the skin creates a gap, the epithelial cells of the skin, surrounding the wound, move in a concerted fashion to close this gap. The boundaries of these gaps can have different ...

Insulin is synthesized in significant quantities only in beta cells in the pancreas. Since it is a protein or a polypeptide structure it is synthesized like most other proteins via transcription and ...

Just as folds are important in the ancient art of origami, they are also vital for the function of many proteins. Mutations in a protein associated with conditions such as seizures and autism spectrum ...