Aging can begin with an imperceptible restructuring of the "internal factories" of the cell. Scientists have learned that ...

Researchers have proposed a novel integrated framework to understand the complex progression of autoimmune skin diseases. A ...

As we age, our cells don’t just wear down—they reorganize. Researchers found that cells actively remodel a key structure called the endoplasmic reticulum, reducing protein-producing regions while ...

Cells shrink a major internal structure as they age. New research shows this downsizing is deliberate—and linked to longer lifespan.

The endoplasmic reticulum is usually the biggest organelle in eukaryotic cells and is invovled in many crucial processes... | Cell And Molecular Biology ...

Researchers describe a new way by which cells adapt to the aging process: by actively remodeling the endoplasmic reticulum, ...

Improvements in public health have allowed humankind to survive to older ages than ever before, but, for many people, these ...

Using high-speed, nanoscopic imaging, researchers directly observed autophagosomes transferring from the endoplasmic ...

Researchers are debating whether ERAP2 can serve as a reliable ageing-derived biomarker for premature ovarian insufficiency, reflecting underlying biological ageing.

Janelia researchers have uncovered a novel way that two of the structures inside cells-the endoplasmic reticulum (ER) and lysosomes-coordinate the production of proteins, highlighting how interactions ...

Defective macrophage efferocytosis is a key driver of chronic nonresolving inflammation in dyslipidemia-associated diseases, such as obesity and atherosclerosis. However, the mechanism by which ...