Nuclei were isolated using the 10X Genomics Assay for Transposase Accessible Chromatin Nuclei Extraction from fresh tissues protocol CG000212. Chromium Single Cell Next GEM ATAC Solution (10X Genomics ...

"Nucleosomes carry all the genetic information inside the nucleus of the eukaryotic cell. Chromatin remodelers help the cell access and propagate that information," said co-first author Deepshikha ...

"Nucleosomes carry all the genetic information inside the nucleus of the eukaryotic cell. Chromatin remodelers help the cell access and propagate that information," said co-first author Deepshikha ...

But archaea do not have a nucleus, and their small circular genomes are easier to package inside their cells. “If the primary role for chromatin is not packaging ... is analogous to the state of the ...

A eukaryote is any cell or organism that possesses a clearly defined nucleus. Eukaryotic cells form the foundation of complex, multicellular life, including apple trees, mushrooms, fish and humans.

Non-Commercial (NC): Only non-commercial uses of the work are permitted. Background: the sophisticated cellular heterogeneity of cell populations in glioblastoma (GBM) has been a key factor ...

A generalizable Hi-C foundation model for chromatin architecture, single-cell and multi-omics analysis across species. bioRxiv, 2024. Paper @article{wang2024hicfoundation, title={A generalizable Hi-C ...

Complex mechanisms regulate gene dosage throughout eukaryotic life cycles ... life cycle history and gene dosage in a broader range of organisms. The reproductive cells of organisms that reproduce ...

The course gives a comparative introduction on the size, structure and organisation of eukaryotic genes and genomes, and put an emphasis on the functional significance of a genomes organisation and ...