Identifying the underlying causes of prolonged lung inflammation associated with radiographic abnormalities could be key understanding long COVID and other lung conditions, researchers say.
A new study demonstrates how AlveoliX’ Lung-on-Chip model offers a more accurate and predictive approach to investigating respiratory diseases and testing potential treatments. AMYRA successfully ...
The effort by the Center for Regenerative Medicine of Boston University, Boston Medical Center, and GSK aims to find new ...
In the first 2 weeks after bleomycin exposure, the mice develop alveolar as well as interstitial fibrosis (Peng et al., 2013). Gene expression at days 1 or 2 (inflammation); 7 or 14 (acute fibrosis) ...
These cells include alveolar type 2 (AT2 ... model will enable studying the basic causes of diseases like pulmonary fibrosis, as well as the testing of potential new drugs, according to the ...
Moreover, the severity of CT scan changes correlated with the abundance of neutrophils and a type of macrophage called monocyte-derived alveolar macrophage, or MoAM. A higher abundance of MoAMs ...
The authors first showed that patients with idiopathic PF or bleomycin-treated wild-type mice express more citrullinated histone H3 (citH3) than controls. This observation aligns with studies citing ...
Pulmonary fibrosis, including its most common form ... epithelial cells initiate and perpetuate the disease, including alveolar type 2 (AT2) cells, which are responsible for maintaining the ...
Liver fibrosis is scarring of the liver. It has many causes, including alcohol-induced damage, infections, and diseases that harm the liver. Inflammation and injury of the liver can lead to scarring, ...
It concerns alveolar epithelium ... Prolonged ILD may result in pulmonary fibrosis, but this is not always the case. Idiopathic pulmonary fibrosis is one form of "interstitial lung disease".