On Wednesday, Aileron Therapeutics Inc (NASDAQ; ALRN) revealed topline data from Cohort 2 of its Phase 1b trial of safety and ...

6). There was marked interalveolar fibrosis, and the alveolar walls blended with the interstitial fibrous tissue. Giant-cell reaction to the concretions was present, most of the giant cells being ...

These cells include alveolar type 2 (AT2 ... model will enable studying the basic causes of diseases like pulmonary fibrosis, as well as the testing of potential new drugs, according to the ...

Identifying the underlying causes of prolonged lung inflammation associated with radiographic abnormalities could be key understanding long COVID and other lung conditions, researchers say.

[29] These differences are distinguishable by their distribution and pattern of cellularity and fibrosis as well as by their degree of homogeneity. Familial clustering of CFA does occur ...

An international study has identified two types of these so-called dysbioses in cystic fibrosis. They display ... Landmark Study Involving Babies in Ireland Supports Use of Cystic Fibrosis Drug in ...

Specifically, they studied the association between idiopathic pulmonary fibrosis and transforming growth factor beta 1, ...

Pulmonary fibrosis, including its most common form ... epithelial cells initiate and perpetuate the disease, including alveolar type 2 (AT2) cells, which are responsible for maintaining the ...

High-dose LTI-03 (5 mg BID), a Caveolin-1 related peptide, reduced expression of multiple profibrotic proteins in both ...

Alveolar macrophages need to be stimulated ... In the long-term, the disease can lead to serious complications, including lung fibrosis and the need for a lung transplant. About Savara Savara ...