An FDA-designated orphan drug that can target a key vulnerability in lung cancer shows promise in improving the efficacy of ...

HR underlies many DNA repair processes ... fusion–bridge cycle could also be caused by any repeated non-homologous recombination process without repeated breakage and fusion 55.

The yeast RGG motif-containing RNA binding protein Scd6 and its human ortholog LSM14A regulate the translation of specific ...

Blacksmith Medicines, Inc. (Blacksmith), a leading biopharma dedicated to discovering and developing therapeutics targeting metalloenzymes, today announced the company will present data on its ...

Sydney: Australian researchers have found that DNA repair may determine how cancer ... by radiation was repaired by a method called homologous recombination, they found that cancer cells died ...

QIAGEN N.V. (NYSE: QGEN; Frankfurt Prime Standard: QIA) today announced a series of product and partnership updates designed ...

“We now have several biomarkers to guide therapy in advanced prostate cancer such as homologous recombination DNA repair defects for PARP inhibitors, defective mismatch repair for pembrolizumab ...

April 9, 2025 First-line talazoparib plus enzalutamide versus placebo plus enzalutamide in men with metastatic castration-resistant prostate cancer and homologous recombination repair ... Rare ...

A research team has unveiled a crucial mechanism that helps regulate DNA damage repair, with important implications for improving cancer treatment outcomes. The result was published in Cell Death ...

Mutations fuel evolution while also causing diseases like cancer. Epigenome-targeted DNA repair can help organisms protect important genomic regions from mutation. However, the adaptive value, ...