The human body is made up of billions of cells. These cells grow and divide through a process called cell division. There are ...

During meiosis, at least one crossover is selectively generated per pair of homologous chromosomes through homologous recombination to ensure their faithful segregation. The molecular mechanisms ...

It has long been recognised that temperature affects meiotic crossover rates in a variety of species and that extreme high temperature can disrupt meiosis, leading to ... of why temperature affects ...

However, meiosis requires crossing over ... fusion–bridge cycle could also be caused by any repeated non-homologous recombination process without repeated breakage and fusion 55.

1997). A limited subset of DSBs must engage the homologous chromosome as a recombination partner and be repaired as a crossover event to forge a physical connection between homologs that facilitates ...

2019; Farini and De Felici, 2022). The proper completion of meiosis is essential for fertility and for ensuring the normal development of the offspring (Farini and De Felici, 2022). Therefore, ...

Meiotic recombination is the driving force of evolutionary development and an important source of genetic variation. The meiotic recombination does not take place randomly in a chromosome but occurs ...

Now, researchers have uncovered the details of one likely mechanism -- heating a tumor inhibits homologous recombination, a DNA repair system, so cancer cells cannot mend DNA damaged by radiation or ...