Aileron Therapeutics' Phase 1b trial shows LTI-03 improved biomarkers and reduced SPD levels, indicating the potential to ...

(RTTNews) - Aileron Therapeutics, Inc. (ALRN), Wednesday announced positive topline data from the cohort 2 of Phase 1b study evaluating LTI-03 in patients with idiopathic pulmonary fibrosis (IPF).

The topline data showed ISM001-055 to have improved the forced vital capacity (FVC) of IPF patients studied 12 weeks after ...

In a small Phase IIa trial, Insilico’s generative AI-designed idiopathic pulmonary fibrosis drug improved lung function and ...

PULMONARY alveolar microlithiasis ... Bilateral "Ground-Glass" Appearance of Both Lung Fields, with the Minute Particles of Calcium Densely Demarcated in the Lung Structure. Both lung fields ...

Accordingly, this study highlights the potential use of composite biomarkers mechanistic screening for compound-induced lung fibrosis. Biomarkers of pulmonary fibrosis have been identified using ...

Structure Therapeutics Inc ... Thus, a patient who has idiopathic pulmonary fibrosis has scarring/damage to the lungs with no known root cause. In essence, it just comes about randomly.

Kolb has received payment from Avalyn Pharma for providing advice for the MIST trial; has received research funding for preclinical work from Boehringer Ingelheim, United Therapeutics, and Structure .

In sarcoidosis, fibrosis in affected organs, especially the lungs and heart, accounts for most of the long-term morbidity and mortality that is directly attributable to sarcoidosis itself (rather than ...

Mike, who used to work as a delivery driver, was experiencing breathlessness for several months before doctors discovered pulmonary fibrosis — which causes scarring in the lungs — this May.

Emily Pink, 21, has cystic fibrosis, a rare genetic disorder that causes a build-up of sticky mucus in her lungs and digestive system. She remembers a childhood filled with hospital stays brought ...

The primary goal of the research will be to understand how dysfunctional lung epithelial cells contribute to causing and perpetuating pulmonary fibrosis, according to the release. These cells ...