The topline data showed ISM001-055 to have improved the forced vital capacity (FVC) of IPF patients studied 12 weeks after ...

The development of a novel, artificial intelligence (AI)-generated biotechnology has the potential to transform care options ...

Peer-to-Peer (P2P) applications share resources and communicate in a decentralized or distributed architecture. Often application nodes communicate directly with each other or cooperate to do work ...

Among histologic risk factors, stage 3 (adjusted Hazard ratio (aHR) 2.68, 95% confidence interval (CI) 1.18–6.11) and stage 4 (aHR 6.96, 95% CI 3.55–13.64) fibrosis were associated with ...

Revised: This Reviewed ... of peer review; the eLife assessment and the public reviews have been updated where necessary by the editors and peer reviewers. This study retrospectively analyzed clinical ...

1 State Key Laboratory Cell Differentiation and Regulation, Henan International Joint Laboratory of Pulmonary Fibrosis ... potentially influencing the progression of organ fibrosis. This review ...

Idiopathic hypersomnia (IH) is, in many ways, a mystery. Its cause is unknown. Only one FDA-approved treatment exists. Even diagnosing this disorder, which brings excessive sleepiness in the ...

with FDA Breakthrough Therapy designation and peer-reviewed validation, supporting a "Strong Buy" rating. Denifanstat's unique FASN inhibition mechanism effectively reduces liver fibrosis ...

Podolanczuk AJ, Cottin V. A narrative review of real-world data on the safety of nintedanib in patients with idiopathic pulmonary fibrosis. Adv Ther. 2023;40(5):2038-2050. doi:10.1007 ...

It was previously documented that lysosomal localization of the Lysosomal transmembrane proteins LAPTM4 or 5 (including LAPTM4b) is regulated by Nedd4 family ubiquitin ligases, and independently, that ...

The UK Royal Society has more experience of peer review than most publishers, with the practice used by its journals for nearly 200 years. Last month, the society unsealed more than 1,600 ...