Major depressive disorder (MDD) remains a formidable global health challenge, with standard pharmacological and psychological treatments proving inadequate for a substantial subset of patients.

Scientists have identified two specific types of brain cells that behave differently in people with depression, offering a clearer picture of what is happening inside the brain. By analyzing donated ...

Folate (also known as B-9) is a vitamin that is necessary for, among other things, the formation of red blood cells, protein metabolism, cell growth and division, and prevention of neural tube defects ...

See more of our trusted coverage when you search. Prefer Newsweek on Google to see more of our trusted coverage when you search. Depression remains an ongoing problem in the U.S. as historically high ...

Menopause and Depression: What’s the Link? Hormonal changes during your menstrual cycle can be linked to an increased risk for depression. That includes the hormone fluctuations of perimenopause, ...

Auvelity is a medicine for major depressive disorder, commonly known as depression. It was approved by the FDA in 2022. It is an oral tablet that contains a combination of two medicines called ...

Lotus Kay started to feel depressed when she was 12 years old. But when she got her first period about a year later, a peculiar pattern emerged: Her depression symptoms would get worse the week before ...

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...