As such, they are orienting the RESET-Myositis trial to focus on two cohorts of patients: those with dermatomyositis or antisynthetase syndrome, and those with immune-mediated necrotizing myopathy.

Overall, 10 patients have been treated with C-CAR168 including 7 LN patients, 1 Secondary Progressive Multiple Sclerosis (SPMS), 1 Neuromyelitis Optica Spectrum Disorder (NMOSD) and 1 Immune ...

Myositis is classified into several subtypes based on the underlying immune mechanisms and clinical characteristics, including dermatomyositis, or DM, antisynthetase syndrome, or ASyS, and immune ...

"We have identified a group of patients with a necrotizing myopathy and a novel anti-200/100 autoantibody specificity," said Dr. Andrew Mammen, M.D., Ph.D., and lead author of the study.

The FDA designation also includes study of the therapy for active severe/refractory idiopathic inflammatory myopathy (IIM, an autoimmune disease that causes muscle weakness, inflammation and pain), ...

--Allogene Therapeutics, Inc., a clinical-stage biotechnology company pioneering the development of allogeneic CAR T products for cancer and autoimmune disease, today announced that ALLO-329, an ...

Idiopathic myopathies include polymyositis, dermatomyositis, non-specific myositis, and necrotizing myopathy. 1 These are very rare conditions and may be missed if one is unfamiliar with the ...

Nipocalimab (M-281) is under development for the treatment of moderate to severe bullous pemphigoid (BP), moderate to severe active rheumatoid arthritis (RA), chronic inflammatory demyelinating ...

On December 13th, Gregory Charles Harrass entered his eternal rest following an eight year long battle against necrotizing myopathy and cirrhosis of the liver. He is survived by the love of his ...

A memorial benefit for Jon Peterson will be held from 11 a.m. to 2 p.m. Sunday, Oct. 20, at Labby's, 1100 19th Ave. N., Fargo. Proceeds from the free-will lunch, silent, online, and live auctions ...

Five of the main subtypes include dermatomyositis, anti-synthetase syndrome, immune-mediated necrotizing myopathy, polymyositis, and overlap myositis, all of which can lead to significant ...