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A huge row has broken out around former Chief Justice of India DY Chandrachud’s continued stay in the official bungalow ...
Electromyography showed irritable myopathy affecting the proximal more than the distal muscles of the upper and lower extremities. Figure 1: Axial T2-Weighted MRI of the lower extremity. Axial ...
The onset is usually insidious and painless and is characterized by progressive symmetric proximal muscle weakness during the course of 3 to 6 months. 3 Patients frequently complain of difficulty ...
Muscular dystrophies (MDs) are an array of inherited disorders characterized by progressive muscle weakness and degeneration. This review explores the genetic foundation, pathophysiological mechanisms ...
Proximal muscle weakness is a unifying feature of each subtype. IMNM is characterized by skeletal muscle weakness due to muscle cell necrosis. ASyS is characterized by muscle inflammation, ...
At the microscopic level, colchicine causes a vacuolar myopathy characterized by myofibrillar disorganization and accumulation of autophagic vacuoles in muscle fibers.
As much as 43% of patients with systemic sclerosis demonstrate evidence of myopathy, while those with proximal weakness and higher creatine kinase exhibit worse function and survival, according to ...
CK was 2560 IU/l (normal <290). Plain films of the hands revealed cystic bony change. EMG demonstrated features consistent with a necrotising myopathy. MRI of proximal muscle groups revealed abnormal ...
The hallmark symptom is symmetric proximal muscle weakness (PM) which may occur with characteristic skin findings (DM). Once suspected clinically, the diagnosis of PD/DM typically involves a ...
Practically all types of myopathy result in weakening and atrophy of skeletal muscles – particularly those closest to the center of the body (also known as the proximal muscles), such as the ...
The clinical presentation of anti-HMGCR myopathy overlaps with limb-girdle muscular dystrophy (LGMD), as both present with proximal, symmetric, progressive muscle weakness and elevated creatine kinase ...