Bipolar disorder (BD) is a chronic mental health condition characterized by recurrent episodes of depression and mania. It poses a substantial burden on global health, with an increasing incidence.

Researchers have identified hyperactivity in the reticular thalamic nucleus as a driver of autism-like behaviors in mice. This brain region, which gates sensory information, was found to be overactive ...

Not revised: This Reviewed Preprint includes the authors’ original preprint (without revision), an eLife assessment, public reviews, and a provisional response from the authors. The manuscript by ...

This valuable research identifies Smim32 as a new genetic marker for the claustrum and generates transgenic mouse lines aimed at enhancing specificity when studying this brain region. However, the ...

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ABSTRACT: Objective: Sleep dysfunctions are common in schizophrenia, yet few evidence-based guidelines exist for the detection, diagnosis and management of sleep disturbances in this disorder. This ...

BOSTON – People often experience headaches and body pain after a lack of sleep, but the mechanisms behind this phenomenon are unclear. A new study led by investigators at Massachusetts General ...

Summary: Researchers discovered how sleep deprivation can exacerbate pain. Their study demonstrates that a neurotransmitter, N-arachidonoyl dopamine (NADA), decreases in a brain region called the ...

Sleep deprivation (SD) causes several adverse functional outcomes, and understanding the associated processes can improve quality of life. Although the effects of SD on neuronal activity in several ...