Synaptic transmission is the biological process ... Genetically encoded dense core vesicle markers, compatible with immunohistochemistry and expansion microscopy, enable single-vesicle resolution ...

A recent study published in Psychophysiology provides new insights into how stimulating the vagus nerve through the ear might ...

The study introduces new tools for measuring the intracellular calcium concentration close to transmitter release sites, which may be relevant for synaptic vesicle fusion and replenishment. This ...

The laboratory of Ege Kavalali, professor and chair of the Department of Pharmacology, published a paper in Nature ...

Synaptic pruning is a crucial neurodevelopmental process through which the brain refines its neural circuitry by systematically eliminating excess or weak synaptic connections. During early ...

Moreover, the protein's effects on endocytosis, exocytosis, and vesicle circulation are closely related to synaptic transmission. In the central nervous system, the release of calcium-dependent ...

First discovered as proteins found on synaptic vesicles and at the presynaptic plasma membrane, SNAREs are members of a family of highly conserved proteins that reside on vesicles (v-SNAREs ...

Herein, we propose a protocol combining metabolomics profiling from plasma extracellular vesicles (EVs) and machine learning to identify the metabolomics discrepancies of early gastric cancer ...

Moreover, the study revealed that these neurons have a more complex morphology and altered synaptic connections to their neighbors, which could explain why they are overactive. The researchers ...

It turns out that these fatty messenger molecules are transported in fatty vesicles. This surprising discovery contrasts with how traditional messenger molecules move. Dopamine and serotonin ...

Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095, United States Department of Bioengineering, University of California, Los Angeles, California 90095, ...

In a development for artificial intelligence, researchers have unveiled a synaptic device array that shows promise for enhancing artificial visual systems. This innovative array, measuring a compact 0 ...