Certain DNA sequences can form structures other than the canonical double helix. These alternative DNA conformations—referred ...

Testing SMA patient DNA with advanced methods like HapSMA can reveal genetic changes that affect how severe the disease is, ...

Understanding the material basis of adaptive evolution has been a central goal in biology dating back to at least the time of ...

SynGAP Research Fund (SRF), dba Cure SYNGAP1, the leading patient advocacy group dedicated to improving the lives of those ...

The last few years have provided us with a new level of understanding of how chromosomes are replicated, segregated and read - and how their 3D organisation influences expression of individual genes ...

A new study combines genetic data and improved computational tools to look more closely at GWAS results for both adult-onset and childhood-onset asthma. The research identified many genetic variants ...

UChicago study combines genetic data with computational models to pinpoint likely genetic variations which cause asthma onset ...

Genome wide association studies (GWAS) have identified hundreds of genome regions containing thousands of genetic variants associated with asthma, but it's still not clear which variants have an ...

This study provides valuable findings on the role of site-specific DNA methylation changes during spermatogenesis and their contribution to paternal epigenetic inheritance. The study proposes that ...

Correspondence to Dr Minna Männikkö, Northern Finland Birth Cohort Studies, Faculty of Medicine, Aapistie 5 / P.O. Box 5000, 90014 University of Oulu, Finland; minna.ruddock{at}oulu.fi Background Low ...